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Follistatin 315 Peptide

Follistatin 315 antibody
Physical State: Lyophilized Powder
Synonyms: FST315 , FS, Activin-binding protein.
Appearance: Sterile Filtered White Lyophilized (Freeze-Dried)
Purity (by HPLC): 99.00%
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Volume Before Lyophilized:500ul
Concentration(mg/ml):1.0mg/ml
Purity:85% by SDS-PAGE
Packing: 1mg / vial

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  • Specifications

Follistatin 315 Description:

Follistatin 315 FST is a single chain gonadal protein that specifically inhibits follicle stimulating hormone release. The single FST gene encodes two isoforms Follistatin 317 and Follistatin 315 containing 317 and 315 amino acids respectively, resulting from alternative splicing of the precursor mRNA.

In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-315 of the FST-315 protein.

Follistatin 315 Benefits:

1) Follistatin 315 / FST works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth.

2) Follistatin 315 / FST promote muscle growth due to the unique mechanism of action, FST joint use of steroids, IGF has better results. It only acts on muscle tissue, after use will not cause the proliferation of other tissue cells.

Follistatin 315 Application:

Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.

Follistatin works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth.

In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH).

High FSH levels in men may indicate that testicles are not functioning correctly; This condition limits muscle growth, recovery, and normal hormonal function. However, FSH levels that are too low can also negatively impact health and reproductive capabilities.

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