AICAR (Acadesine) Bodybuilding Application it’s an important pharmacological research agent, used principally as an AMPK activator. It’s a compound which has shown extremely impressive fat-loss and endurance-enhancing effects in laboratory animals. As a matter of fact, AICAR works best as part of an endurance stack, and it has been used by athletes as a performance enhancing compound in sports, where …

Andarine S4 is a Selective Androgen Receptor Modulator (SARM) developed by GTx. Like all SARM’s S4 was developed in the treatment of muscle wasting diseases with benign prostatic hypertrophy treatment also being high on the list of possible treatment benefits. Andarine is not as strong as some of the other SARM’s in terms of an anabolic effect that leads to …

Sunifiram (DM-235) is a synthetic derivative of Piracetam, although due to breaking the pyrrolidone backbone it is no longer in the Racetam class of drugs (yet by being derived from them, it is still commonly associated with this class). Sunifiram Applications: Sunifiram is one of the newest nootropics on the market to smart drugs family. It is considered to be …

LGD-3303 like LG121071, was developed by Ligand Pharmaceuticals. The chemical structure of LGD-3303 resembles that of LGD-4033, another SARM developed by Ligand Pharmaceuticals.LGD 3303 is NOT Anamorelin. It is the most potent SARM we have seen personally to date! LGD 3303 – Most Anabolic SARMs powder? There has been a lot of confusion about LGD 3303 being the growth hormone …

LGD-4033 (Ligandrol) is a novel non-steroidal oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity. It’s in a class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. LGD-4033 (Ligandrol) is expected to produce the therapeutic benefits of …

Descriptions about YK11 YK-11 is a synthetic, steroidal selective androgen receptor modulator (SARM). It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR. The drug has anabolic activity in vitro in C2C12 myoblasts …

RAD140 (Testolone) شرح: RAD140 is a highly effective, oral SARM currently being studied for both anabolic and neuroprotective effects. It is in a class of androgen receptor (AR) ligands that are tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. Recent research of RAD140 shows superior lean tissue selectivity, and reduced …

GW0742 is a highly selective and potent PPAR delta agonist. It is currently sold for research purposes under a license from GlaxoSmithKline. PPAR delta agonists are nuclear receptor proteins that play critical roles in regulating human metabolism, cell development, and cell differentiation. Product Function Reduces Gut Inflammation Improves Heart Health Helps With Diabetes Improves Lipid Profile Prevents Hypertension

Basic Information about Cardarine Endurobol GW-501516 GW501516 (also known as GW-501,516, GW1516, GSK-516 and Endurobol, is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the …

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters …

SR9009 Benefits Promotes the healing of ligaments, tendons, bones as well as old injuries Stimulates loose skin to tighten Promotes lean muscle mass Increases the oxidation of fat SR9009: A Drug That Might Cause A Major Breakthrough in Fitness The drug was developed by Professor Thomas Burris who found that it was capable of reducing obesity in animal models, particularly …

What is MK-1775? MK-1775 is an inhibitor of the checkpoint kinase Wee1 (IC50 = 5.2 nM).1 It has been shown to inhibit the phosphorylation of Cdc2 at tryosine-15, which abrogates the G2 DNA damage checkpoint.1 In p53-deficient tumors that rely solely on the G2 checkpoint upon DNA damage, MK-1775, in combination with DNA-damaging chemotherapeutic agents, is reported to induce apoptosis …