CAS : 139755-83-2
Chemical Formula: C22H19N3O4
Masse moléculaire: 389.4
Content: 99.5% Sildenafil citrate, Viagra
Solubility: Slightly soluble in water, methanol; very slightly soluble in ethanol, chloroform
Apparence: Poudre cristalline blanche
Stockage: ombres, conservation confinée.
Usage: Viagra (Sildenafil citrate) is a drug used to treat erectile dysfunction (impotence) in males and pulmonary arterial hypertension (PAH).
Sildenafil citrate, sold as Viagra, Sildenafil is an oral drug for the treatment of ED, Utilisé dans le traitement de la dysfonction érectile et de l'éjaculation prématurée, La déficience de la fonction érectile et l'éjaculation prématurée ont des améliorations très significatives. Il y a plus 1500 Documents pour prouver les différentes causes d'impuissance éjaculation prématurée,savait que le taux de réussite est supérieur 80%, et montrer son effet curatif fiable, grâce à l'utilisation de plus de 20 millions de personnes dans le monde, prouvé sa stabilité à long terme, la sécurité de 25 à 60 Minutes de fonction de travail pour coïncider avec un temps nécessaire pour les préliminaires, connaissait l'ajustement du temps dans le temps de concentration de médicament le plus élevé, Aidez le mari et la femme une vie sexuelle satisfaisante.
The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension. It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, à son tour, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the United States Food and Drug Administration (FDA), and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-mg tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
