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Mifepriston CAS:84371-65-3

Mifepristone
CAS : 84371-65-3
Molekylär formel: C29H35NO2
Molekylvikt: 429.65
Smältpunkt: 195-198 Degree C
Utseende: Light yellowish powder
Use: Used for a variety of allergic skin diseases and cosmetic additives
Analysera: 99%

förfrågan
  • Specifikationer

Mifepriston är en syntetisk steroidförening med både antiprogesteron- och antiglukokortikoidegenskaper. Föreningen är en 19-nor-steroid med substitutioner i positionerna C11 och C17 (17 beta-hydroxi-11 beta-[4-dimetylaminofenyl] 17 alfa-[1-propynyl]extra-4, 9-dien-3-on), som antagoniserar kortisolverkan kompetitivt på receptornivå.

Mifepriston är en progesteronreceptorantagonist som används som abortmedel under de första månaderna av graviditeten, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist,

Mifepristone plays a role on the receptor level of new antifertility drugs, no progesterone, androgen, estrogen activity. It has an effect on softening and dilating uterine neck. It is a new antiprogesterone, and anti-glucocorticoid activity, without progesterone, estrogen, androgen and estrogen activity. And progesterone receptor affinity is 5 times stronger than progesterone. For termination of early pregnancy, reinstating menstruation and terminating pregnancy, fetal death, etc. In induction of labor.

Mifepristone is used alone or in combination with misoprostol (Cytotec) to end an early pregnancy. Early pregnancy means it has been 49 days or less since your last menstrual period began. Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy.

Mifepristone is also available as another product (Korlym), which is used to control hyperglycemia (high blood sugar) in people with a certain type of Cushing’s Syndrome in which the body makes too much of the hormone cortisol. This monograph only gives information about mifepristone (Mifeprex), which is used alone or in combination with another medication to end an early pregnancy. If you are using mifepristone to control hyperglycemia caused by Cushing’s syndrome, read the monograph entitled mifepristone (Korlym) that has been written about this product.

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