Kina steroider pulver / GBL / Peptider / HGH
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Andra steroider

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De protesterade med CAS:168273-06-1

CAS: 168273-06-1
Molekylär formel: C22H21Cl3N4O. ClH
Molekylvikt: 500.25
Utseende: Vitt eller nästan vitt kristallint pulver
Renhet: 99% by HPLC
Smältpunkt: 272.25 ℃
Användande: Pharmaceutical intermediates, fine organic synthesis and catalyst, health care products etc

förfrågan
  • Specifikationer

Rimonabant (Acomplia) var den första i en ny klass av terapeutiska medel som kallas Cannabinoid-1 Receptor Blockers (CB1). Acomplia studerades för användning vid behandling av fetma och relaterade tillstånd.

En experimentell underdrog, Rimonabant, hjälper dig gå ner i vikt, sluta röka och det hjälper också till att skydda ditt hjärta. Det har försök visat 33% av människor på Rimonabant förlorade 10% of body weight and kept their weight down for two yearsthis is a record, no other diet drug has managed to keep a person’s weight down for so long. The second 33% lost 5% of body weight and kept it down. As well as keeping you lean, the drug also helps you quit the smoking habit. This will be of great interest for many smokers who are afraid to give up because they say they will put on loads of weight if they do.

Rimonabant has also been shown to be a μ-opioid receptor antagonist (possibly the contributing factor in its reported dysphoric qualities).Its main effect is reduction in appetite.

1. Obesity:
In a 2006 (2 year) study reported in JAMA, “Compared with the placebo group, the 20 mg of rimonabant group produced greater mean (SEM) reductions in weight (-6.3kg vs -1.6kg; P<.001), waist circumference (-6.1cm vs -2.5cm; P<.001), and level of triglycerides (percentage change, -5.3vs 7.9; P<.001) and a greater increase in level of high-density lipoprotein cholesterol (percentage change, 12.6vs 5.4; P<.001).”

2. Smoking cessation:
Rimonabant may also be found to be effective in assisting some smokers to quit smoking. Sanofi is currently conducting studies to determine the possible value of rimonabant in smoking-cessation therapy. The Studies with Rimonabant and Tobacco Use (STRATUS) program involves more than 6,000 subjects.

STRATUS is designed to explore two smoking-related therapies: first, to use rimonabant directly to aid in smoking cessation; second, to help prevent weight gain in former smokers. Initial results apparently suggest rimonabant is effective for both uses. i alla fall, the FDA has explicitly stated to Sanofi that, without additional studies, rimonabant cannot be approved in the United States for smoking cessation therapy.

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