Yohimbine HCL CAS:65-19-0

Yohimbine är en indolalkaloid som härrör från barken på trädet Pausinystalia yohimbe i Centralafrika. Det är ett veterinärmedicinskt läkemedel som används för att vända sedering hos hundar och rådjur. Yohimbine har studerats som en potentiell behandling för erektil dysfunktion men det finns inte tillräckligt med bevis för att bedöma dess effektivitet. Extracts from yohimbe have been marketed as dietary supplements for improving sexual function.

Yohimbine is a pre-synaptic alpha 2-adrenergic blocking agent. The exact mechanism for its use in impotence has not been fully elucidated. i alla fall, yohimbine may exert its beneficial effect on erectile ability through blockade of central alpha 2-adrenergic receptors producing an increase in sympathetic drive secondary to an increase in norepinephrine release and in firing rate of cells in the brain noradrenergic nuclei. Yohimbine-mediated norepinephrine release at the level of the corporeal tissues may also be involved. För övrigt, beneficial effects may involve other neurotransmitters such as dopamine and serotonin and cholinergic receptors.

Yohimbine is a drug used in veterinary medicine to reverse the effects of xylazine in dogs and deer. Yohimbe extracts, which contain yohimbine, have been used in traditional medicine and marketed as dietary supplements.

Yohimbe is taken by mouth arouse sexual excitement, for erectile dysfunction (ED), sexual problems caused by medications for depression called selective-serotonin reuptake inhibitors, and general sexual problems in both men and women. It is also used for athletic performance, weight loss, exhaustion, chest pain, high blood pressure, low blood pressure that occurs when standing up, diabetic nerve pain, and for depression along with certain other medications.

Yohimbe contains a chemical called yohimbine which can increase blood flow and nerve impulses to the penis or vagina. It also helps counteract the sexual side effects of certain medications used for depression.