Basic Information about Cardarine Endurobol GW-501516 GW501516 (also known as GW-501,516, GW1516, GSK-516 and Endurobol, is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the …

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters …

SR9009 Benefits Promotes the healing of ligaments, tendons, bones as well as old injuries Stimulates loose skin to tighten Promotes lean muscle mass Increases the oxidation of fat SR9009: A Drug That Might Cause A Major Breakthrough in Fitness The drug was developed by Professor Thomas Burris who found that it was capable of reducing obesity in animal models, particularly …

What is MK-1775? MK-1775 is an inhibitor of the checkpoint kinase Wee1 (IC50 = 5.2 nM).1 It has been shown to inhibit the phosphorylation of Cdc2 at tryosine-15, which abrogates the G2 DNA damage checkpoint.1 In p53-deficient tumors that rely solely on the G2 checkpoint upon DNA damage, MK-1775, in combination with DNA-damaging chemotherapeutic agents, is reported to induce apoptosis …

Enobosarm, better known as Ostarine or MK 2866, is a Selective Androgen Receptor Modulator (SARM) developed by GTx (GTx-024) to combat muscle wasting and osteoporosis. Many speculate Ostarine may find uses in hormone replacement treatment plans, as well as in the treatment of sarcopenia, cachexia and muscle atrophy. This is a highly valuable benefit to those suffering from muscle wasting …