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Oksitosin CAS:50-56-6

Oxytocin
Alias:Atonin,Endopituirina,Orasthin,Oxytocinum,Partocon,Pitocin,Piton,Pitupartin,Utedrin,Uteracon
Cas No.: 50-56-6
EINECS : 200-048-4
Moleküler formül: C43H66N12O12S2
Moleküler ağırlık: 1007.19
Saflık (HPLC): 98.0%min.
Dış görünüş: Beyaz toz
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): >80.0%
Water Content(Karl Fischer): <6.0%
Acetate Content(HPIC): <12.0%
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Seviye : Farmasötik Sınıf
Storage: Closed, below 2 ~ 8℃ preservation

soruşturma
  • Özellikler

Kullanım : For induction of labor, postpartum oxytocin, and abortion due to uterine atony or retraction caused by the bad uterus bleeding; understand the placental function reserve (oxytocin challenge test); nasal drops can promote milk ejection.

Oxytocin (Oxt) is a mammalian neurohypophysial hormone. Produced by the hypothalamus and stored and secreted by the posterior pituitary gland, oxytocin acts primarily as a neuromodulator in the brain.

Oxytocin plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes, in particular during and after childbirth; its name, meaningswift childbirth”, comes from Greek, oksysswift” ve , tokosbirth.It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, ve, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.

Başvuru:

Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced ergometrine as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release. The tocolyticagent atosiban (Tractocile) acts as an antagonist of oxytocin receptors; this drug is registered in many countries to suppress premature labor between 24 ve 33 weeks of gestation. It has fewer side effects than drugs previously used for this purpose (ritodrine, salbutamol, and terbutaline).

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