Sildenafil Mesilat CAS:131543-23-2

Kullanım: İlaç hammaddeleri, afrodizyak İlaç tedavisinin hammaddesidir, Erektil disfonksiyon tedavisinde endikedir.

Sildenafil Mesilat, Sildenafil ile aynı tipte bir inhibitördür 5 -cGMP fosfodiesteraz, penis ereksiyonuna yol açan korpus kavernozumdaki kas hücrelerini gevşetir ve yumuşatır. Bu gevşemeye siklik guanozin monofosfat aracılığıyla nitrik oksit aracılık edebilir. Farmasötik malzeme, hormon. As a cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) selective inhibitor, penile smooth muscle relaxation allows rapid erection. Sildenafil is cheap, is the development and production of low-cost classes available kidney yang-like the perfect material for medicine and health products.

In 16 separate 4-24 week trials of men (over 18 years old) who suffered from impotence for longer than 6 months, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfi* treatment compared to the placebo group.

Erections were improved in 72% of group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mgs. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates.