11-Ketotestosterone CAS:564-35-2

Adrenosterone is a steroid hormone with weak androgenic effect first isolated in 1936 from the adrenal cortex. Adrenosterone occurs in trace amounts in humans as well as most mammals and in larger amounts in fish, where it is a precursor to the primary androgen, 11-ketotestosterone. Adrenosterone has shown to be converted into 11-ketotestosterone in humans, which contributes to adrenosterone’s androgenic effects.

Adrenosterone’s main action is it lowers cortisol levels. Cortisol is the main catabolic (muscle-eating) hormone and it also promotes fat gain. Cortisol and testosterone also work in an inverse relationship, so high cortisol levels lower testosterone. Adrenosterone acts as a competitive inhibitor, preventing cortisone from attaching to the 11b-hydroxysteroid dehydrogenase type I reductase. By competing at the receptor, it keeps cortisone from attaching and converting to cortisol through the enzyme. Adrenosterone naturaliter in corpore invenitur et a glandulis adrenalibus liberatur. Corpus eo utitur ut via ad gradus cortisoli ordinandos adiuvet.