11-OXO known as adrenosterone, is a prohormone produced in the adrenal glands.
11-OXO is a prohormone and it’s conversion hormone is known as 11-ketotestosterone , which is quite an interesting hormone, being a mild androgen in humans and a sex steroid in fish. 11-oxo is a non-aromatizing analogue of Testosterone, which causes dry lean gains and fat loss, along with an increased sexual desire.
11-oxo’s conversion to 11-ketotestosterone in humans is much of what contributes to it’s noticeable androgenic effect in the user.11-Keto-androstenedione or 11-keto-androstenetrione are trademark names for this hormone, while the correct name would be androst-4-ene-3,11,17-trione., however this article we will mostly refer to it as 11-oxo.
This is where 11-OXO really shines, in fact 11-OXO is rarely used on it’s own, it’s commonly stacked with other compounds. Due to it’s non-methylated design, 11-OXO can be stacked with virtually any popular designer steroid or pro-hormone. Most users stacking 11-OXO with other compounds are primarily doing so to control cortisol levels and reduce bodyfat, while allowing the other compound to increase strength and size gains, users stacking 11-OXO with other compounds should stick to lower dosages i.e 300mg-600mg. Below is a short list of several compounds 11-OXO is commonly stacked with.
Adrenosterone’s main action is it lowers cortisol levels. Cortisol is the main catabolic (muscle-eating) hormone and it also promotes fat gain. Cortisol and testosterone also work in an inverse relationship, so high cortisol levels lower testosterone. Adrenosterone acts as a competitive inhibitor, preventing cortisone from attaching to the 11b-hydroxysteroid dehydrogenase type I reductase. By competing at the receptor, it keeps cortisone from attaching and converting to cortisol through the enzyme. Adrenosterone is found naturally in the body and is released by the adrenal glands. The body uses it as a way to help regulate cortisol levels.
