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Esteroides trembolona

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Tibolona CAS:5630-53-5

Brand Name: Livial, Tibofem
Número CAS: 5630-53-5
Fórmula: C21H28O2
Masa molar: 312.446 g/mol
Ensayo: 99% Min.
Personaje: White Powder
Policy: Re-Shipping Policy
Transport Package: Very Discreet, as Required
Delivery: 5-7 Working Days Door to Door
Leading Time: Within 12hours After Payment
Powder: Sí
Origen: China
Certificación: YO ASI 9001, USP

investigación
  • Presupuesto

Tibolone is a synthetic steroid drug with estrogenic, progestogenic, and weak androgenic actions which was introduced in 1988 and is used widely in Europe, Asia, Australasia, y, with the exception of the United States (where it is not available), the rest of the world.

It is used mainly for treatment of endometriosis,as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile.It has also been investigated as a possible treatment for female sexual dysfunction.

Tibolone is the first of a class of compounds known as the selective tissue oestrogenic activity regulators. It is structurally related to 19-nortestosterone derivatives and exhibits weak oestrogenic, progestogenic and androgenic activities. Tibolone itself has no biological activity. The diverse hormonal effects of tibolone result from the action of several key metabolites on various tissues.

Tibolone is primarily metabolised into δ4,3β-hydroxy and 3α-hydroxy isomers. These isomers have different binding affinities for oestrogen, progesterone and androgen receptors1. The 3α?hydroxy and 3β-hydroxy metabolites bind solely to the oestrogen receptor, whereas the δ4 isomer has affinity for the progesterone and androgen receptors, but not for the oestrogen receptor.

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